Clinical Trials

The physicians at Mount Nittany Physician Group - Urology are dedicated to providing high quality care and improving the urologic health of our patients. This includes the ability to offer our patients further treatment options with the newest investigational medications and treatments being researched today. Clinical Research provides the patients in our community with access to cutting edge treatments, which may not otherwise be available to them.

New medicines, treatment options and technology are being introduced everyday to help improve our quality of life. You or a loved on may be asked to consider participating in a research study to evaluate these potential breakthroughs in medical science. Participating as a study volunteer is one way to contribute to the advancement of medical research.

A "clinical trial" is a type of research study or scientific investigation that is done to help doctors learn more about new ways to prevent, diagnose or treat a disease. This type of research involves human beings who choose to volunteer to participate in the research study. The research study may also be done to find out if the drug or device being researched is safe and effective for people to use.

The participants in research studies perform a very valuable service. However, before enrolling, it is a good idea to know what is expected and what is going to take place throughout the clinical trial. Be sure to ask questions and discuss any concerns you might have with the research staff.

To learn more about research and clinical trials available at Mount Nittany Physician Group - Urology, call 814.231.6824 today.

You may also find out more information about volunteering for a clinical trial by clicking on the links below:

Prostate Cancer

Now enrolling: clinical research study for metastatic prostate cancer.
You're fighting back
. We're working to enhance your body's ability to do the same. The PROSPECT study is evaluating the potential effectiveness of an investigational vaccine-based immunotherapy for metastatic prostate cancer. The investigational vaccine - administered through a series of injections over a period of five months - is designed to teach the body's immune system to identify and destroy prostate cancer cells. To learn more, contact Karen Smith, RN, clinical research coordinator, at 814.231.6824 or

Visit and

Overactive Bladder

Is your overactive bladder a problem?  Do you have to go to the bathroom often?

Learn more about a medical research study assessing two approved medications and placebo for overactive bladder.

To qualify, you must meet the following criteria:

  • You must be 18 years of age or older
  • You have the need to urinate frequently throughout the day and experience a sudden urge to urinate for at least the past 6 months
  • You must be taking or previously taken at least one oral medication for your overactive bladder and not done well with it

Other criteria will be assessed to confirm if you can participate.

For additional information, download the brochure or contact Karen Smith, RN, clinical research coordinator, at 814.231.6824 or


If you are living with multiple sclerosis...are you in control of your bladder, or is your bladder in control of you?

If you’re a person living with multiple sclerosis and are suffering with urinary leakage, you may want to consider taking part in a medical research study.

You must meet the following criteria:

  • 18 years or older
  • Stable multiple sclerosis for three months
  • Have had urinary leakage for at least three months
  • Have used at least one overactive bladder medication
  • Not using clean-intermittent self-catheterization (CIC) or an indwelling catheter to manage your urinary leakage

The DIGNITY2 study is assessing a new investigational dosage of an approved medication to control urinary incontinence (leakage) as a result of the bladder problems that can occur in people with multiple sclerosis.

For more information, download the participant leaflet, visit, or contact Karen Smith, RN, clinical research coordinator, at 814.231.6824 or

STRIVE Clinical Trial

Do you or does someone you care about have recurrent prostate cancer? If so, please consider taking part in the STRIVE Clinical Trial for patients whose cancer may or may not have spread beyond the prostate and who have progressed on hormonal therapy. In STRIVE, patients will be randomized (flip of a coin) to receive either enzalutamide or bicalutamide (a standard medication for this condition).

For more information, download the brochure or contact Karen Smith, RN, clinical research coordinator, at 814.231.6824 or